Identification of some metabolites produced by endophytic fungi of grapevine in Zanjan province

Authors

1 Department of Plant Protection ,Agricultural Research, Education and Extension Organization (AREEO), Ardabil, Iran

2 College of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran

3 Department of Plant Protection, College of Agriculture, Zanjan University, Zanjan, Iran

4 Department of Plant Protection, College of Agriculture, University of Tabriz, Tabriz, Iran

Abstract

Endophytes include microorganisms such as fungi and bacteria that live in healthy plant tissues without causing symptoms or disease. These microorganisms exist in a symbiotic relationship with their host plant, producing a wide range of metabolites that contribute to the overall survival of the plant. The aim of this study was to investigate some metabolites produced by endophytic fungi in grapevine orchards in Zanjan province. For this purpose, samples were collected from grapevine orchards in Zanjanprovince during October to November 2017. The identification of fungal isolates was based on morphological characteristics and ITS-rDNA sequence data for selected isolates. As endophytes produce various metabolites in their hosts, they possess divers chemical structures such as alkaloids, terpenoids, quinones, peptides, xanthones, acid have fatty acids and phenolic compounds. Some of these metabolites including D-Homoandrostane (5α,13α), Eicosane, Heneicosane, Hexadecane, Octadecane, Octadecanoic acid, Pentadecanoic acid, Tetracosane, Tetradecanoic acid, Tetradecanethiol, α-Muurolene, Methyl 16-methyl-heptadecanoate were traced and identified in this research by fungal species Cytospora viticola, Epicoccum nigrum and Microsphaeropsis olivacea. These metabolites possess antimicrobial, anticancer, antioxidant, antibiotic and antifungal properties.

Keywords



Articles in Press, Corrected Proof
Available Online from 30 April 2026
  • Receive Date: 30 July 2025
  • Revise Date: 28 December 2025
  • Accept Date: 09 February 2026